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Q: I sometimes take tramadol for rheumatoid arthritis although I do not like the side effects. But my doctor says it is best to stay on something non-addictive for as long as possible and as long as the arthritis does not progress zoloft lyrics further. This has been about 4 years now. My dose has gradually increased to 2 50mg tablets 4-6 times a day. I am noticing that I have a lot of involuntary muscle movements. Nothing major, sort of just a twitch. Is this normal?A: Ultram tramadol 25mg tablets (tramadol) is a narcotic-like medication used to treat tramadol 25mg tablets pain, which lists "uncontrollable shaking of a body part" as a side effect. The tramadol 25mg tablets medication was created as an alternative to addictive narcotics, but the metabolite (what it breaks down into) can cause dependence in some people. Other common side effects tramadol 25mg tablets may include dizziness/drowsiness, headache, insomnia, nervousness, muscle tightness, sweating, dry mouth, heartburn, nausea, vomiting, constipation, diarrhea, and itching. This is not a complete list of the side effects associated with Ultram (tramadol). Patti Brown, PharmDQ: Does tramadol cause itching?A: Ultram (tramadol) is a pain medication that does list itching as a side effect, but taking the antihistamine, Benadryl (diphenhydramine), may prevent the unwanted side effect. Benadryl (diphenhydramine) can cause drowsiness, so it should be taken at bedtime. Other side effects of Ultram (tramadol) may include nausea, vomiting, heartburn, diarrhea, constipation, dizziness, drowsiness, weakness, headache, changes in mood, sweating, dry mouth, and chills. This is not a complete list of the side effects associated with Ultram (tramadol). For more specific information, consult with your doctor or pharmacist for guidance based what is klonopin used to treat on your health status and current medications, particularly before tramadol 25mg tablets taking any tramadol 25mg tablets action. When your doctor prescribes a new tramadol 25mg tablets medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health care provider about any negative side effects from prescription drugs. You can also report them tramadol 25mg tablets to the U.S. Food and Drug Administration by visiting www.fda.gov/medwatch or by calling 1-800-FDA-1088. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Patti Brown, PharmDQ: I take tramadol for pain and it doesn't really help. Can I stop taking it?A: Tramadol tramadol 25mg tablets is a narcotic-like pain reliever commonly used to treat moderate to severe pain. Tramadol should be taken exactly as prescribed by your physician. Follow the directions on your prescription. Take your tramadol dose with a full glass of water with or without food. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Do not change your dose without talking to your doctor. Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. For more information on tramadol, visit our Web site //www.everydayhealth.com/drugs/tramadol. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jennifer Carey, tramadol 25mg tablets PharmDQ: Is tramadol addictive?A: Tramadol (Ultram) is an opioid-like analgesic used to treat moderate to moderately-severe pain. The most common side effects from tramadol are dizziness, headache, drowsiness, constipation, and nausea. Although tramadol may not be as addictive as some stronger pain medications, tramadol does have addictive potential. According to the prescribing information tramadol should be avoided in patients that are addiction prone. It also states that tolerance or dependence may result from extended use. Patients who have been on tramadol for an extended length of time should not discontinue the medication abruptly or they may experience withdrawal symptoms. The dose should be tapered down slowly before stopping completely. Your doctor can provide you with a taper schedule if they feel you should stop tramadol. This is not a complete list of the side effects associated with Tramadol. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Laura Cable, PharmD., BCPSQ: Is tramadol an opiate?A: Ultram (tramadol) (//www.everydayhealth.com/drugs/tramadol) is a non-narcotic pain reliever. Tramadol binds to some opioid receptors and inhibates the reuptake of norepinephrine and serotonin (neurotransmitters in the brain). Tramadol may be habit-forming and should be used only by the person it was prescribed for. Tramadol should be taken exactly as how the doctor prescribed. Do not take more medication than the doctor prescribed. Side effects of tramadol include dizziness, drowsiness, blurred vision, and sleep problems such as insomnia. (//www.everydayhealth.com/arthritis/osteoarthritis/index.aspx). When your doctor prescribes a new medication, be sure to discuss all your prescription medications and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals and herbals, as well as foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescriptions and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and advise you about drug interactions and side effects. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kimberly Hotz, PharmD.Q: I'm taking tramadol 37.5 - 325. Is this 37.5 milligrams?A: The combination it looks like you are describing is Ultracet. Ultracet is a combination of the pain relievers, tramadol and acetaminophen. The combination of acetaminophen and tramadol is used to treat moderate to severe pain. The strength refers to 37.5 mg (milligrams) of tramadol and 325 mg of acetaminophen. You may also find helpful information at //www.everydayhealth.com/drugs/acetaminophen-tramadol. Sarah Lewis, PharmDQ: I take tramadol daily for chronic lower back pain. I've just had a hysterectomy and have been given another pain medication. Does the tramadol nullify the effect of the other pain reliever?A: Depending on what the specific other pain medication is, the combination of two pain medications could have some specific interactions. Check with your physician as to whether you should be taking both pain medications simultaneously. Don't stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Lowell Sterler, RPhQ: What is the recommended Ultram dose?A: Ultram (tramadol) is a non-narcotic pain reliever, similar in action to the narcotic pain relievers. Ultram is indicated for the management of moderate to moderately severe pain in adults. The recommended Ultram dose should be individualized according to patient need and should be initiated and maintained using the lowest beneficial dose. Experience with Ultram has demonstrated that starting with the lowest dose and titrating upward to an effective dose results in fewer discontinuations and increased patient tolerability. According to the prescribing information, the recommended Ultram dose for initiation of therapy should be 25 mg per day in the morning and titrated in increments of 25 mg as separate doses every three days until a dose of 100 mg per day (25 mg four times daily) is achieved. If necessary, the daily dose may then be titrated up, based on patient tolerability, by 50 mg every three days until a dose of 200 mg per day (50 mg four times daily) is achieved. After titration has been completed, the recommended Ultram dose can range from 50 to 100 mg and is administered as needed for pain every 4 to 6 hours. The maximum daily dose of Ultram should not exceed 400 mg per day. Essentially, this means it is important not to exceed 8 tablets daily. Ultram may be taken with or without food. It is important to avoid alcohol while taking Ultram. Ultram may be habit-forming. Therefore, it is essential to take it exactly as directed by your doctor. To avoid unpleasant withdrawal symptoms, do not abruptly discontinue taking Ultram. Appropriate discontinuation of treatment with Ultram should only be done under the supervision tramadol 25mg tablets of your physician. Some of the side effects, possible with Ultram treatment, include dizziness, nausea, constipation, headache, somnolence, vomiting, pruritus, weakness, sweating, dyspepsia, dry mouth and diarrhea.Q: Can Ultram cause serotonin syndrome?A: http://Ultram (tramadol) is a narcotic-like pain reliever. Ultram is approved for the management of moderate to moderately severe pain. The extended-release formulation of Ultram is indicated for the management of moderate to moderately severe chronic pain when around the clock treatment is required. According to the prescribing information, serotonin syndrome has been reported in patients taking Ultram. Serotonin syndrome may occur within the recommended dose of Ultram. However, Ultram related serotonin syndrome occurred in less than one percent of patients during clinical trials and/or post marketing research. Although there is a risk for serotonin syndrome while taking Ultram alone, it is more likely to occur with the concomitant use of other serotonergic drugs. Serotonin syndrome is a potentially life-threatening medical condition, which can be fatal if left untreated. According to the National Institutes of Health (NIH), serotonin syndrome most often occurs when a patient takes two medications that affect serotonin levels. Serotonin syndrome may develop with the concomitant use of Ultram and other serotonergic medications, such as the triptans (medications used to treat migraine headaches), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) or monoamine oxidase inhibitors (MAOIs). Serotonin syndrome may also occur, and caution is advised, in patients being also being treated with the antibiotic linezolid, lithium or St. John's Wort. Signs and symptoms of serotonin syndrome include mental status changes, such as agitation or hallucinations, tachycardia, fluctuating blood pressure, hyperreflexia, incoordination, fever, shivering, tremor, sweating, nausea, vomiting, diarrhea, seizures and coma. Seek immediate medical attention if you experience any signs and symptoms associated with serotonin syndrome. If you are currently taking any of the above medications, speak to your health care provider before beginning treatment with Ultram to prevent possible drug interactions and to avoid the development of serotonin syndrome.Q: What are the common Ultram side effects?A: http://Ultram (tramadol) is a centrally acting synthetic opioid analgesic. Ultram is not a narcotic pain reliever and not classified as a controlled substance. The mechanism of action of Ultram is not fully understood. The action of Ultram is similar to narcotic pain relievers. Ultram is indicated for the management of moderate to moderately severe pain in adults 17 years of age and over. The use of Ultram in pediatric patients is not recommended. The most frequently reported adverse reactions were related to the central nervous system (CNS) and gastrointestinal system. Some of the common Ultram side effects, possible with treatment, include dizziness/vertigo, nausea, constipation, headache, somnolence, vomiting, pruritus, CNS stimulation (nervousness, anxiety, agitation, tremor, spasticity, euphoria, emotional instability and hallucinations), weakness, sweating, dyspepsia, dry mouth and diarrhea. Another common Ultram side effect is impaired mental or physical ability to perform potentially hazardous tasks including operating machinery or driving a motor vehicle. Patients are cautioned against engaging in any potentially hazardous tasks while taking Ultram. There are several warnings, or less common Ultram side effects, associated with treatment. Seizures have been reported in patients being treated with Ultram within the recommended dosage range. According to post marketing research, the risk of seizures is increased with higher doses of Ultram, above the recommended dosage range. The seizure risk is also increased in patient taking Ultram concomitantly with selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) or other tricyclic medications, such as cyclobenzaprine or promethazine, other opioids, monoamine oxidase inhibitors (MAOIs), neuroleptics or other medications that reduce the seizure threshold. The risk of convulsions may also be increased in patients with epilepsy, a history of seizures, or in patients who already have a risk for seizures, such as head trauma. There is also a suicide risk possible with Ultram treatment. According to the prescribing information, Ultram should not be given to patients who are addiction-prone or suicidal. Furthermore, Ultram should be used with caution in patients concomitantly taking tranquilizers, antidepressants, use alcohol in excess or who have been diagnosed with emotional disturbance or depression. Ultram related deaths have occurred in these populations of patients. Serotonin syndrome is possible with treatment with Ultram alone. However, serotonin syndrome is more likely to occur when Ultram is concomitantly administered with other serotonergic medications, such as SSRIs, TCAs, MAOIs, serotonin norepinephrine reuptake inhibitors (SNRIs), the triptans (medications used in the treatment of migraine headaches), linezolid, lithium or St. John's Wort. Serotonin syndrome is a potentially life-threatening medical condition, which can lead to death if left untreated. Serotonin syndrome, related to Ultram treatment, occurred in less than one percent of patients during clinical studies and/or post marketing experience. Signs and symptoms of serotonin syndrome may include mental status changes, tachycardia, fluctuating blood pressure, hyperreflexia, fever, shivering, tremor, sweating, nausea, vomiting, diarrhea, seizures and coma. Seek immediate medical attention if you develop any signs and symptoms of serotonin syndrome. Another less common Ultram side effect, possible with treatment, is allergic reaction which may include pruritus, hives, difficulty breathing, swelling of the face, lips, tongue or throat, or a red, blistering, peeling skin rash. Allergic reactions related to Ultram are serious and rarely fatal and, often times, occurs following administration of the first dose. Patients who are have experienced allergic reactions to codeine or other opioids should not take Ultram. Consult with your health care provider regarding the risks versus benefits of treatment with Ultram and more specific information regarding the common Ultram side effects.Q: How does tramadol affect the liver?A: Tramadol (Ultram) is a non-narcotic opioid analgesic medication. Tramadol works similarly to narcotic pain relievers to manage moderate to moderately severe pain in adults. The action of tramadol to alleviate pain is not fully understood. Tramadol is extensively metabolized (broken down in the body), following oral administration, by several pathways in the liver, including the cytochrome P450 enzymes CYP2D6 and CYP3A4. As a result of the metabolism of Ultram in the liver, by CYP 2D6 and CYP 3A4, there are potential drug interactions. Drug interactions are possible with the concomitant administration of Ultram with medications that are CYP 2D6 and CYP 3A4 inhibitors, such as ketoconazole, erythromycin, quinidine, fluoxetine, paroxetine and amitriptyline. These medications may potentially reduce the metabolism of Ultram and increase the risk for serious adverse reactions, including seizures and serotonin syndrome. In patients with hepatic dysfunction, such as advanced cirrhosis of the liver, the metabolism of Ultram is reduced. According to the prescribing information, in patients who have cirrhosis of the liver, adjustment of the Ultram dosing regimen is recommended. The usual recommended dose of Ultram is 50 mg to 100 mg administered as needed for pain every four to six hours. In patients with cirrhosis of the liver, the recommended dose is 50 mg administered as needed for pain every 12 hours.Q: What is Ultram 50 mg?A: Ultram (tramadol) 50 mg is a centrally-acting, narcotic-like, opioid pain reliever. Ultram acts like narcotic pain relievers in the body. Ultram 50 mg is not a controlled substance. Ultram 50 mg is approved for the management of moderate to moderately severe pain in adults. The safety and efficacy of Ultram 50 mg has not been established in the pediatric population, therefore, it is not recommended for use in children 16 years of age and younger. The dose of Ultram can range from 50 to 100 mg and is administered as needed for pain every 4 to 6 hours. The maximum daily dose of Ultram should not exceed 400 mg per day. Therefore, the daily dose of Ultram should not to exceed 8 tablets. Ultram may be taken with or without food. Patients are advised to avoid alcohol while taking Ultram. Ultram may be habit-forming, so it is essential to take it exactly as directed by your doctor. To avoid unpleasant withdrawal symptoms, do not abruptly discontinue taking Ultram. Appropriate discontinuation of treatment with Ultram should only be under the supervision of your physician. Some of the commonly reported adverse reactions associated with treatment with Ultram 50 mg may include dizziness, nausea, constipation, headache, somnolence, vomiting, itching, nervousness, anxiety, tremor, euphoria, hallucinations, emotional instability, weakness, sweating, indigestion or heartburn, dry mouth and diarrhea. More serious adverse reactions are possible with Ultram 50 mg. Warnings and risks associated with Ultram 50 mg include seizure, suicide, serotonin syndrome, respiratory depression, and anaphylactic reactions. Ultram 50 mg has the potential to interact with central nervous system (CNS) depressants. If Ultram must be administered along with CNS depressants, caution is advised and a reduced dosage of Ultram may be necessary. Ultram 50 mg increases the risk of CNS and respiratory depression in patients receiving CNS depressants including alcohol, opioids, anesthetic medications, narcotics, phenothiazines, tranquilizers, or sedative hypnotics. Additive CNS depression is possible when Ultram is concomitantly used with these other medications and dangerous side effects may occur. For more specific information regarding the risk versus benefit of treatment with Ultram 50 mg, consult with you health care provider.Q: What are the side effects of Ultram ER?A: Ultram ER (tramadol) is a centrally acting synthetic analgesic in an extended-release formulation. Ultram ER is a non-narcotic pain reliever, similar in action to the narcotic pain relievers. Ultram ER is indicated for the management of moderate to moderately severe chronic pain in adults when around the clock treatment is warranted. The exact mechanism of action of Ultram ER to alleviate pain is not clearly defined. The side effects of Ultram ER appear to be dose dependent. During clinical trials, the frequency of adverse reactions, experienced by patients, generally increased with increasing doses from 100 mg to 400 mg. Some of the frequently reported side effects of Ultram ER include dizziness, nausea, constipation, headache, somnolence, flushing, pruritus, vomiting, insomnia, dry mouth, diarrhea, and weakness. More serious side effects with Ultram ER are possible. Risks, or warnings, associated with Ultram ER treatment include seizures, suicide, serotonin syndrome, anaphylactic reactions and respiratory depression. Ultram ER may impair a patient's mental or physical abilities necessary for performing hazardous tasks, including operating machinery or driving a motor vehicle. Ultram ER may be habit-forming and withdrawal symptoms may occur with abrupt discontinuation of treatment. Symptoms of withdrawal from Ultram ER may include anxiety, sweating, insomnia, rigors, pain, nausea, tremors, diarrhea, or upper respiratory symptoms. Patients are advised against abrupt discontinuation of treatment with Ultram ER. According to the prescribing information, withdrawal symptoms may be reduced by appropriately tapering Ultram ER under the supervision of a health care provider. Patients should be advised that Ultram ER is intended for single-dose administration in a 24-hour period. The daily dose of Ultram ER should not exceed 300 mg per day. Doses that exceed what is recommended may result in respiratory depression, seizures and death.Q: Does tramadol cause weight loss?A: http://Tramadol (Ultram) is a synthetic opioid pain reliever, similar in action to the narcotic pain relievers. Tramadol is not a narcotic and not a controlled substance. It is unclear exactly how tramadol works in the body to alleviate pain. Tramadol is approved for the management of moderate to moderately severe pain in adults 17 years of age and older. During the clinical trials of Ultram, the brand-name of tramadol, in patients with chronic nonmalignant pain, tramadol did not cause weight loss. However, the most frequently reported adverse reactions were in the central nervous system and gastrointestinal system. Some of the reported adverse reactions, related to the gastrointestinal system, include nausea, vomiting, constipation, dyspepsia, diarrhea and anorexia. The cumulative effects of these reactions may potentially cause weight loss. Tramadol does not directly cause weight loss tramadol 25mg tablets and is not indicated to be used for weight loss purposes. Tramadol may cause other side effects including dizziness, headache, somnolence, pruritus, nervousness, anxiety, euphoria, emotional instability, hallucinations, weakness, sweating and dry mouth. Tramadol may impair the ability to perform potentially hazardous tasks including operating machinery or driving a car. Tramadol may cause more serious reactions. More serious side effects associated with tramadol are less common but may potentially include seizures, serotonin syndrome, respiratory depression, suicide and anaphylaxis, a potentially life-threatening allergic reaction.Q: I am taking tramadol 300 mg daily. How do I stop taking it without side effects?A: Tramadol (Ultram) is a medication used to treat pain. It is classified as a centrally acting opioid analgesic. Ultram is a non-narcotic pain reliever which works similar to narcotics. This means that Ultram works in the brain and spinal cord, much like morphine, and relieves pain. Ultram is a medication that must not be stopped abruptly because it can cause withdrawal symptoms. Ultram withdrawal can be extremely unpleasant and you do not want to stop taking this medication on your own. Your health care provider can provide you with the safest rate at which to decrease your dose that will help minimize any side effects of withdrawal. Consult with your health care provider regarding safe discontinuation of Ultram. Lori Poulin, PharmDQ: I have been on tramadol for 3-4 tramadol 25mg tablets years now, and I am taking 300 to 400 mg per day. Is this harmful for my health?A: http://Chronic pain can be difficult to manage and if the cause of the pain is unable to be treated, the symptoms of pain may be well-controlled with the use of Ultram (tramadol) which is a medication used to manage moderate to severe pain. Ultram (tramadol) is eliminated mostly through the kidneys, but also goes through the liver, so your doctor should periodically monitor their tramadol 25mg tablets function. Ultram (tramadol) was developed as an answer to avoiding dependence to pain medication, which opiates can have, but studies have found that the metabolite (what the drug turns into) of Ultram (tramadol) can also create some dependence by the user. Ultram (tramadol) does not help reduce the cause of pain. It just blocks the signal from going to the brain that causes the body to feel pain. The maximum recommended dose is 400 mg per day, so if using it alone does not provide adequate relief, other medications can be used with Ultram (tramadol) to help manage the pain. For instance, if there is throbbing pain from tight muscles, a muscle relaxant, such as Flexeril (cyclobenzaprine) or Zanaflex (tizanidine) may be beneficial. NSAIDs (non steroidal anti-inflammatory drugs), such as Aleve (naproxen) or Motrin/Advil (ibuprofen) can be added to help reduce pain caused from swelling. If there is sharp shooting pain from the nerves, a medication, such as Neurontin (gabapentin) or Lyrica (pregabalin) may stop the nerves from firing. Your doctor will know the best pain management therapy for you specific situation and may also add physical therapy, chiropractic work, or other non-drug related therapy as well. Patti Brown, PharmDQ: Does tramadol aggravate the liver?A: Tramadol (Ultram) is a medication used to treat moderate to moderately severe pain. Tramadol is an opioid-like analgesic. The metabolism of tramadol is reduced in patients with liver dysfunction. It is recommended to decrease the dose of tramadol in patients with liver problems. Some of the most common side effects associated with tramadol include flushing, dizziness, headache, drowsiness, insomnia, itching, constipation, nausea, vomiting, upset stomach and weakness. The prescribing information for tramadol does list hepatitis and liver failure as rare potential side effects. Tramadol can affect the ability to perform tasks that require mental alertness such as driving, do not drive or operate machinery until you know how tramadol will affect you. Alcohol should be avoided in patients taking tramadol. Alcohol can increase the side effects of tramadol and alcohol also has negative effects on the liver. Tramadol may be taken with or without food. Tramadol can cause dependence, for those who wish to stop taking tramadol, the dose should be tapered down slowly to prevent withdrawal symptoms. Talk to your doctor about how to taper the dose if you need to stop taking tramadol. Be sure to inform your doctor and pharmacist of all the medications you take, including over the counter medications, vitamins, and herbal supplements so they can monitor for drug interactions. It is also important to discuss any adverse effects from medications with your doctor. Laura Cable, PharmDQ: What are the side effects of Tramadol and potential drug interactions?A: Tramadol (Ultram) is a centrally-acting pain reliever that is used to relieve moderate to moderately severe pain in adults. The most common side effects of Tramadol are dizziness, nausea, constipation, headache and tiredness. Tramadol may affect alertness and the ability to react, so patients should use caution when engaging in potentially hazardous tasks such as driving a car or operating heavy machinery. Alcohol or other drugs, like opioids, anesthetic agents, narcotics, phenothiazines, tranquilizers or sedative hypnotics that depress the central nervous system can increase these side effects and should not be used in combination with tramadol. Tramadol may also cause seizures. The risk of seizures is increased in people who have a seizure disorder or who are taking antidepressants or other opioid (or narcotic) pain relievers. Antidepressants and other drugs that affect serotonin can lead to a potentially life-threatening reaction, serotonin syndrome, with Tramadol. Serotonin syndrome is marked by mental-status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular aberrations (e.g., hyperreflexia, incoordination) and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea).This is not a complete list of the side effects or drug interactions associated with tramadol. Michelle McDermott, RPh, PharmDQ: Can tramadol cause dreams or nightmares?A: Tramadol is a narcotic-like pain reliever commonly used to treat moderate to severe pain. Common side effects associated with tramadol can include dizziness, drowsiness, weakness, nausea, vomiting, constipation, loss of appetite, blurred vision, and insomnia. This is not a complete list of side effects associated with tramadol. There were no reports of scary or unusual vivid dreams. If you find these dreams bothersome, contact your doctor. Tramadol should be taken exactly as prescribed by your physician. Follow the directions on your prescription. Take your tramadol dose with a full glass of water with or without food. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Do not change your dose without talking to your doctor. Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication, particularly before taking any action. Jennifer Carey, RPh, PharmDQ: Does tramadol show up in rapid strip drug screens?A: http://Ultram (tramadol) is a medication used to manage pain, and although there are specific tests developed to detect the medication, the chance if it showing up on a rapid strip drug screen depends on which version is being used by the facility. The most basic version will not show Ultram (tramadol) as an opiate. It is not a typical opiate, but it does bind to the opiate receptors in the CNS (central nervous system) to block the pain signal. It also blocks the reuptake of norepinephrine and serotonin, which can further help to block the pain signal from reaching tramadol 25mg tablets the brain. The medication was developed as an answer to the older, traditional, but addictive opiates, but the metabolite (what the medication breaks down into) has been found to also cause some addiction as well. It is always best to let an employer, or whoever the testing is being conducted for, know all of the medications you are taking, especially prescription medication. Ultram (tramadol) is legally available by prescription only in the United States. The half-life, which is how long it takes until medication is at half the level in the system, which is considered to be when it is no longer at a dose high enough to provide any benefit, of Ultram (tramadol) is approximately 5-6 hours, but the metabolite will add on another 9 hours. However, the medication will still show up on a urine test, that is made to look for it, for approximately 2-4 days. Ultram (tramadol) comes in an immediate release version, but there is also an extended release version that will stay in the system even longer. Patti Brown, PharmDQ: Why do I have such a hard time sleeping now that I take tramadol for pain?A: Ultram (tramadol) is a medication that is used to treat moderate to moderately severe pain. It is classified as a centrally acting synthetic opioid analgesic which means that it works in the brain and spinal cord, much like morphine, and relieves pain. According to the prescribing information for tramadol, sleeping problems were reported as a side effect associated with this medication and occurred in up to 13 percent of patients taking the medication. The most common side effects include constipation, nausea, dizziness, headache, drowsiness, nervousness, shakiness, agitation, itching, sweating, indigestion, dry mouth, and diarrhea. If you are experiencing side effects that are affecting your daily activities, it is important to discuss this with your physician. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmDQ: Can tramadol be used for tooth pain?A: Tramadol (Ultram) is a pain medication which has opioid properties. Tramadol is indicated for treatment of moderate to moderately-severe pain. Tramadol could be used for tooth pain along with other pain conditions. Some of the most common side effects associated with tramadol are dizziness, drowsiness, flushing, headache, insomnia, constipation, nausea, and vomiting. Tramadol may be taken with or without food. Patients taking tramadol should avoid alcohol use due to the increased risk of side effects such as dizziness, drowsiness and confusion. Patients on tramadol should avoid doing activities that require mental alertness such as driving or operating machinery until you know how the medication will affect you. Take tramadol as prescribed by your doctor or dentist, do not take more medication then is prescribed. Tell your doctor or dentist if tramadol is not adequately relieving the pain. Be sure to inform your doctor (or dentist) and pharmacist of all the medications you take, including over the counter medications, vitamins, and herbal supplements so they can monitor for drug interactions. Laura Cable, PharmD., BCPSQ: Is it safe to take tramadol every 6 hours for extended period of time?A: Tramadol (Ultram) is classified as a opioid analgesic. Tramadol is approved for the treatment of moderate to moderately severe pain. According to medical references, the recommended dosing for the immediate release formulation of tramadol is 50 to 100 mg every four to six hours with a maximum of 400 mg per day. Tramadol, like any medication has possible side effects, risks and warnings associated with it use. It is difficult to say if it will be "safe" for you individually over an extended period of time. Patients react differently to medications. According to medical references, the most common adverse effects occurring in greater than 10% of studied patients taking tramadol include the following: flushing, dizziness, headache, somnolence, insomnia, pruritus (itching), constipation, nausea, vomiting, dyspepsia (upset stomach) and weakness. These are not all of the possible side effects associated with the use of tramadol. The recommendation is made for you to talk to your physician regarding the questions and concerns that you have about using tramadol for an extended period of time. Jen Marsico, RPhQ: What are the side effects of the long-term use of Ultram?A: Ultram (tramadol) is a narcotic-like pain reliever that is used to treat moderate to severe pain. Common side effects of Ultram include dizziness, drowsiness, weakness, nausea, vomiting, constipation, loss of appetite, blurred vision, flushing, and insomnia. Ultram can cause side effects that impair your thinking and reactions. So, use caution when doing anything that requires alertness. This is not a complete list of side effects that can occur with Ultram. Ultram may be habit-forming, meaning that it is possible to become physically or mentally dependent on this medication. Withdrawal tramadol 25mg tablets side effects can occur if Ultram is stopped suddenly. With any long-term pain treatment, tolerance may develop. Tolerance is the need for more medication in order to achieve the same amount of pain relief. It is a natural process of the body adjusting to pain medication. Tell your doctor if it seems like your pain medication is not working as well as it used to work. Do not stop or change the amount of medication you take without talking to your doctor first. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmDQ: Is tramadol FDA-approved?A: Ultram (tramadol) is FDA-approved since it is a medication that requires a prescription. The United States Food and Drug Administration (FDA) monitors the health and welfare of the American public by regulating food, drugs, and medical devices. When something is declared "FDA-Approved" it means that it is valid, safe, and effective. When dealing with medication, extensive clinical trials must be submitted by drug manufacturers to prove that their product is safe and effective. The FDA also inspects laboratories and facilities where the drugs are manufactured. In order for drugs to be available through prescription, it must receive approval by the FDA. Tramadol has been on the market for a number of years and has safely provided relief to many patients. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Megan Uehara, PharmDQ: How dangerous is it to take tramadol when you have had 2 seizures in the last 3 years?A: Tramadol (Ultram) is a narcotic pain reliever used to treat moderate to severe pain. Some people who have taken tramadol have experienced seizures. Therefore, tramadol should be used with caution in people who have a history of seizures. It is important to notify your doctor before taking this medication. The doctor should weigh the risks and benefits of using tramadol in order to make a decision about whether you should take this medication. Unfortunately, there is no definite percent or amount that a seizure will occur, as some individuals will not be affected and others will. Thus, only your doctor can make the decision as to whether you should take tramadol if you have a history of seizures. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Megan Uehara, PharmDQ: How long does it take for tramadol to leave your system?A: The amount of time it takes to eliminate a drug from the body will depend on the half-life of the medication. The half-life is the amount of time it takes for half the amount of drug to be cleared from the body. Therefore, after one half-life, half of the drug has left in the body. It takes approximately five half-lives to eliminated most of a drug from the body. The half-life of tramadol (Ultram) is about seven hours. Therefore, it can take up to 35 hours to completely eliminate tramadol. This time may be greater if someone has liver problems, kidney problems, or is over the age of 75 years. Tramadol is a pain reliever that is similar to the narcotic analgesics. Tramadol is used to treat moderate to severe pain. Common side effects of tramadol include nausea, vomiting, loss of appetite, constipation, dizziness, drowsiness, blurred vision, and flushing. This is not a complete list of side effects that can occur with tramadol. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmDQ: Will tramadol make your blood pressure drop?

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